HCV core protein-induced down-regulation of microRNA-152 promoted aberrant proliferation by regulating Wnt1 in HepG2 cells.
BackgroundHepatitis C virus (HCV) psithurisme has been reported to regulate cellular microRNAs (miRNAs).The HCV core protein is considered to be a potential oncoprotein in HCV-related hepatocellular carcinoma (HCV-HCC), but HCV core-regulated miRNAs are largely unknown.Our preliminary experiments revealed significant down-regulation of microRNA-152